Key publication
25
Therapeutic Areas
Immune challenges
Key publication
Breaking Barriers: Characterization of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers.
Key publication
Proof of Pharmacology, Safety, and Pharmacokinetics of the Novel TRPA1 Antagonist BI 1839100: A Randomized, Placebo-Controlled, Parallel Group, First-In-Human Study in Healthy Male Participants.
Key publication
Profiling a Neo-Antigen-Driven Immune Response in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Study of the KLH Challenge Model.
Key publication
Impact of oral administration of single strain spp. on immune responses to keyhole limpet hemocyanin immunization and gut microbiota: A randomized placebo-controlled trial in healthy volunteers.
Key publication
Randomized, double-blind, placebo-controlled study to characterize the immune response after repeated Keyhole Limpet Hemocyanin immunizations in healthy volunteers
Key publication
A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis.
Key publication