Key publication
175
Therapeutic Areas
Methods & challenges

Key publication

Transcranial Magnetic Stimulation as a Translational Biomarker in Early-Phase Anti-Seizure Medication Development: A Randomized, Double-Blind, Placebo-Controlled Study in Generalized Epilepsy

Key publication

First-in-Human Safety, Pharmacokinetics, and Pharmacodynamics of VENT-02 Freebase, a CNS-penetrant NLRP3 Inhibitor

Key publication

Cannabidiol Lacks Direct Effect on Cortical Excitability: A Randomized, Double Blind, Placebo Controlled, 3-Way Crossover Trial.

Key publication

Low-dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug-drug interaction study.

Key publication

Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial.

Key publication

Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.

Key publication

The interactive walkway provides fit-for-purpose fall-risk biomarkers in the elderly: Comparison of zolpidem and suvorexant.

Key publication

The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis.

Key publication

Sensitivity of cognitive function tests to acute hypoxia in healthy subjects: a systematic literature review.